Genex Formulas Korea

NICOTINAMIDE-RIBOSIDE-PROTECTS-AGAINST-LIVER-FIBROSIS-INDUCED-BY-CCL4-VIA-REGULATING-THE-ACETYLATION-OF-SMADS-SIGNALING-PATHWAY

KEY FINDINGS: We found NR could prevent liver fibrosis and reverse the existing liver fibrosis. NR inhibited the activation of LX-2 cells induced by TGF-β, activated Sirt1 and deacetylated Smad2/3. Sirt1 knockdown diminished the inhibiting effect of NR on LX-2 cells activation, and increased expressions of acetylated Smads. In conclusion, NR could prevent liver fibrosis via suppressing activation of hepatic stellate cells (HSCs). This protective effect was mediated by regulating the acetylation of Smads signaling pathway.
Keep Reading….

Select the fields to be shown. Others will be hidden. Drag and drop to rearrange the order.
  • Image
  • SKU
  • Rating
  • Price
  • Stock
  • Availability
  • Add to cart
  • Description
  • Content
  • Weight
  • Dimensions
  • Additional information
  • Attributes
  • Custom attributes
  • Custom fields
Click outside to hide the compare bar
상품비교
상품비교 ×
Let's Compare! Continue shopping
Shopping cart close